BDBM50086206 CHEMBL3425606

SMILES: CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(C)cc12

InChI Key: InChIKey=QHZOFEFMRVFNEM-YRNVUSSQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Escherichia coli)	BDBM50086206 (CHEMBL3425606) Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(C)cc12 Show InChI InChI=1S/C21H23ClN4/c1-15-4-10-19-18(14-15)21(23-12-13-26(2)3)25-20(24-19)11-7-16-5-8-17(22)9-6-16/h4-11,14H,12-13H2,1-3H3,(H,23,24,25)/b11-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair