BDBM50086207 CHEMBL3425605

SMILES: CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cccc(C)c12

InChI Key: InChIKey=XJVUZIFVLZOLFM-FMIVXFBMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Escherichia coli)	BDBM50086207 (CHEMBL3425605) Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cccc(C)c12 Show InChI InChI=1S/C21H23ClN4/c1-15-5-4-6-18-20(15)21(23-13-14-26(2)3)25-19(24-18)12-9-16-7-10-17(22)11-8-16/h4-12H,13-14H2,1-3H3,(H,23,24,25)/b12-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair