BDBM50086514 8,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-pyrido[3,2-g]quinoline-2-carbonitrile::CHEMBL335316

SMILES: CC1(C)CCc2cc3c(cc(nc3cc2N1)C#N)C(F)(F)F

InChI Key: InChIKey=LHQICPSUYGARIS-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50086514   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50086514 (8,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...) Show SMILES CC1(C)CCc2cc3c(cc(nc3cc2N1)C#N)C(F)(F)F Show InChI InChI=1S/C16H14F3N3/c1-15(2)4-3-9-5-11-12(16(17,18)19)6-10(8-20)21-14(11)7-13(9)22-15/h5-7,22H,3-4H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory concentration against human androgen receptor (AR) dependent transcriptional activity in cotransfected mammalian CV-1 cells				Bioorg Med Chem Lett 10: 411-4 (2000) BindingDB Entry DOI: 10.7270/Q2K073HH
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50086514 (8,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...) Show SMILES CC1(C)CCc2cc3c(cc(nc3cc2N1)C#N)C(F)(F)F Show InChI InChI=1S/C16H14F3N3/c1-15(2)4-3-9-5-11-12(16(17,18)19)6-10(8-20)21-14(11)7-13(9)22-15/h5-7,22H,3-4H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory concentration against human androgen receptor (AR) dependent transcriptional activity in cotransfected mammalian CV-1 cells				Bioorg Med Chem Lett 10: 411-4 (2000) BindingDB Entry DOI: 10.7270/Q2K073HH
					More data for this Ligand-Target Pair