BDBM50086927 2-{3,5-Dibromo-4''-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-yloxy}-3-phenyl-propionic acid::2-{3,5-Dibromo-4'-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-yloxy}-3-phenyl-propionic acid::CHEMBL26216

SMILES: Cc1oc(nc1-c1ccc(cc1)-c1cc(Br)c(OC(Cc2ccccc2)C(O)=O)c(Br)c1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=HMJWFQLALKQLPM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50086927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50086927 (2-{3,5-Dibromo-4''-[5-methyl-2-(4-trifluoromethyl-...) Show SMILES Cc1oc(nc1-c1ccc(cc1)-c1cc(Br)c(OC(Cc2ccccc2)C(O)=O)c(Br)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C32H22Br2F3NO4/c1-18-28(38-30(41-18)22-11-13-24(14-12-22)32(35,36)37)21-9-7-20(8-10-21)23-16-25(33)29(26(34)17-23)42-27(31(39)40)15-19-5-3-2-4-6-19/h2-14,16-17,27H,15H2,1H3,(H,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
Leadscope, Inc. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of tyrosine phosphatase 1B				J Med Chem 47: 5984-94 (2004) Article DOI: 10.1021/jm0497242 BindingDB Entry DOI: 10.7270/Q2416Z8N
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50086927 (2-{3,5-Dibromo-4''-[5-methyl-2-(4-trifluoromethyl-...) Show SMILES Cc1oc(nc1-c1ccc(cc1)-c1cc(Br)c(OC(Cc2ccccc2)C(O)=O)c(Br)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C32H22Br2F3NO4/c1-18-28(38-30(41-18)22-11-13-24(14-12-22)32(35,36)37)21-9-7-20(8-10-21)23-16-25(33)29(26(34)17-23)42-27(31(39)40)15-19-5-3-2-4-6-19/h2-14,16-17,27H,15H2,1H3,(H,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)				J Med Chem 43: 1293-310 (2001) BindingDB Entry DOI: 10.7270/Q2W958FT
					More data for this Ligand-Target Pair