null
SMILES: C[C@H]1c2cccc3C[C@H]4N(C)CCc5ccc1c(-c23)c45
InChI Key: InChIKey=HGMQRIBEHJQILA-MEDUHNTESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat)) | BDBM50087030 ((1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity against Rat 5-hydroxytryptamine 7 receptor using [3H]-5-HT | J Med Chem 43: 1339-49 (2001) BindingDB Entry DOI: 10.7270/Q2RJ4HQ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50087030 ((1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Displacement of [3H]5-HT from rat SERT | J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50087030 ((1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from rat 5HT1A receptor | J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50087030 ((1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 31.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity was measured on cloned Human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPAT | J Med Chem 43: 1339-49 (2001) BindingDB Entry DOI: 10.7270/Q2RJ4HQ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50087030 ((1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Displacement of [3H]raclopride from rat dopamine D2 receptor | J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50087030 ((1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 39.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity of the compound was measured on cloned Human D2A Receptor which is labeled by [3H]-Raclopride | J Med Chem 43: 1339-49 (2001) BindingDB Entry DOI: 10.7270/Q2RJ4HQ3 | |||||||||||
More data for this Ligand-Target Pair |