BDBM50087060 CHEMBL3426599

SMILES: COc1ccc(cc1OC)-c1c(C)nc2c(NCCNC(C)=O)cc(Cl)nn12

InChI Key: InChIKey=BENVEUQOMWIBNI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50087060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4-kinase type 2-alpha (Homo sapiens (Human))	BDBM50087060 (CHEMBL3426599) Show SMILES COc1ccc(cc1OC)-c1c(C)nc2c(NCCNC(C)=O)cc(Cl)nn12 Show InChI InChI=1S/C19H22ClN5O3/c1-11-18(13-5-6-15(27-3)16(9-13)28-4)25-19(23-11)14(10-17(20)24-25)22-8-7-21-12(2)26/h5-6,9-10,22H,7-8H2,1-4H3,(H,21,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Inhibition of PI4K2alpha (unknown origin) assessed as hydrolysis of ATP for 60 mins by ADP-Glo kinase assay				J Med Chem 58: 3767-93 (2015) Article DOI: 10.1021/acs.jmedchem.5b00499 BindingDB Entry DOI: 10.7270/Q2MW2JVR
					More data for this Ligand-Target Pair