BDBM50087327 6-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl)-2-phenyl-hexanoic acid ethyl ester::CHEMBL288266

SMILES: CCOC(=O)C(CCCCn1cnc2C(O)CNC=Nc12)c1ccccc1

InChI Key: InChIKey=SFSXDAXQZZUSLZ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50087327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine deaminase (Bos taurus (bovine))	BDBM50087327 (6-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]dia...) Show SMILES CCOC(=O)C(CCCCn1cnc2C(O)CNC=Nc12)c1ccccc1 |c:18| Show InChI InChI=1S/C20H26N4O3/c1-2-27-20(26)16(15-8-4-3-5-9-15)10-6-7-11-24-14-23-18-17(25)12-21-13-22-19(18)24/h3-5,8-9,13-14,16-17,25H,2,6-7,10-12H2,1H3,(H,21,22)	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Metabasis Therapeutics Inc. Curated by ChEMBL					Assay Description Evaluated for the inhibition of calf intestinal Adenosine deaminase (ADA)				J Med Chem 43: 1495-507 (2000) BindingDB Entry DOI: 10.7270/Q2Z31XWJ
					More data for this Ligand-Target Pair
AMP deaminase 2 (Homo sapiens (Human))	BDBM50087327 (6-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]dia...) Show SMILES CCOC(=O)C(CCCCn1cnc2C(O)CNC=Nc12)c1ccccc1 |c:18| Show InChI InChI=1S/C20H26N4O3/c1-2-27-20(26)16(15-8-4-3-5-9-15)10-6-7-11-24-14-23-18-17(25)12-21-13-22-19(18)24/h3-5,8-9,13-14,16-17,25H,2,6-7,10-12H2,1H3,(H,21,22)	KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Metabasis Therapeutics Inc. Curated by ChEMBL					Assay Description Evaluated for the inhibition of porcine heart or human L-type Adenosine 5'-monophosphate deaminase (AMPDA)				J Med Chem 43: 1495-507 (2000) BindingDB Entry DOI: 10.7270/Q2Z31XWJ
					More data for this Ligand-Target Pair