BDBM50087419 (E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyquinoline-7-carboxylic acid::2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyquinoline-7-carboxylic acid::2-[2-((E)-3,4-Dihydroxy-5-methoxy-phenyl)-vinyl]-8-hydroxy-quinoline-7-carboxylic acid::2-[2-(3,4-Dihydroxy-5-methoxy-phenyl)-vinyl]-8-hydroxy-quinoline-7-carboxylic acid::CHEMBL36640

SMILES: COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(O)c1O

InChI Key: InChIKey=CLMLBXMNTZEJCB-GORDUTHDSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50087419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(O)c1O Show InChI InChI=1S/C19H15NO6/c1-26-15-9-10(8-14(21)18(15)23)2-5-12-6-3-11-4-7-13(19(24)25)17(22)16(11)20-12/h2-9,21-23H,1H3,(H,24,25)/b5-2+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8076 Curated by ChEMBL					Assay Description In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.				Bioorg Med Chem Lett 14: 2473-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.005 BindingDB Entry DOI: 10.7270/Q2RX9BH1
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(O)c1O Show InChI InChI=1S/C19H15NO6/c1-26-15-9-10(8-14(21)18(15)23)2-5-12-6-3-11-4-7-13(19(24)25)17(22)16(11)20-12/h2-9,21-23H,1H3,(H,24,25)/b5-2+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(O)c1O Show InChI InChI=1S/C19H15NO6/c1-26-15-9-10(8-14(21)18(15)23)2-5-12-6-3-11-4-7-13(19(24)25)17(22)16(11)20-12/h2-9,21-23H,1H3,(H,24,25)/b5-2+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(O)c1O Show InChI InChI=1S/C19H15NO6/c1-26-15-9-10(8-14(21)18(15)23)2-5-12-6-3-11-4-7-13(19(24)25)17(22)16(11)20-12/h2-9,21-23H,1H3,(H,24,25)/b5-2+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Silesia Curated by ChEMBL					Assay Description Inhibition of HIV1 recombinant integrase 3'-processing and strand transfer activity using 21-mer U5B/U5A duplex oligonucleotides after 1 hr				Bioorg Med Chem 19: 5000-5 (2011) Article DOI: 10.1016/j.bmc.2011.06.054 BindingDB Entry DOI: 10.7270/Q2SN0CTM
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(O)c1O Show InChI InChI=1S/C19H15NO6/c1-26-15-9-10(8-14(21)18(15)23)2-5-12-6-3-11-4-7-13(19(24)25)17(22)16(11)20-12/h2-9,21-23H,1H3,(H,24,25)/b5-2+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	708	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase 3' processing activity				Eur J Med Chem 43: 81-92 (2008) Article DOI: 10.1016/j.ejmech.2007.02.021 BindingDB Entry DOI: 10.7270/Q24170XZ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(O)c1O Show InChI InChI=1S/C19H15NO6/c1-26-15-9-10(8-14(21)18(15)23)2-5-12-6-3-11-4-7-13(19(24)25)17(22)16(11)20-12/h2-9,21-23H,1H3,(H,24,25)/b5-2+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Silesia Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase				Bioorg Med Chem 19: 5000-5 (2011) Article DOI: 10.1016/j.bmc.2011.06.054 BindingDB Entry DOI: 10.7270/Q2SN0CTM
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(O)c1O Show InChI InChI=1S/C19H15NO6/c1-26-15-9-10(8-14(21)18(15)23)2-5-12-6-3-11-4-7-13(19(24)25)17(22)16(11)20-12/h2-9,21-23H,1H3,(H,24,25)/b5-2+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris Sud Curated by ChEMBL					Assay Description Inhibition of PIM1				Bioorg Med Chem Lett 20: 2801-5 (2010) Article DOI: 10.1016/j.bmcl.2010.03.061 BindingDB Entry DOI: 10.7270/Q2125STS
					More data for this Ligand-Target Pair