BDBM50087423 (E)-2-(3,4-dihydroxy-5-iodostyryl)-8-hydroxyquinoline-7-carboxylic acid::2-[2-(3,4-Dihydroxy-5-iodo-phenyl)-vinyl]-8-hydroxy-quinoline-7-carboxylic acid::CHEMBL37845

SMILES: OC(=O)c1ccc2ccc(\C=C\c3cc(O)c(O)c(I)c3)nc2c1O

InChI Key: InChIKey=VHVZMHBNQVTTIP-DAFODLJHSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50087423 ((E)-2-(3,4-dihydroxy-5-iodostyryl)-8-hydroxyquinol...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3cc(O)c(O)c(I)c3)nc2c1O Show InChI InChI=1S/C18H12INO5/c19-13-7-9(8-14(21)17(13)23)1-4-11-5-2-10-3-6-12(18(24)25)16(22)15(10)20-11/h1-8,21-23H,(H,24,25)/b4-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087423 ((E)-2-(3,4-dihydroxy-5-iodostyryl)-8-hydroxyquinol...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3cc(O)c(O)c(I)c3)nc2c1O Show InChI InChI=1S/C18H12INO5/c19-13-7-9(8-14(21)17(13)23)1-4-11-5-2-10-3-6-12(18(24)25)16(22)15(10)20-11/h1-8,21-23H,(H,24,25)/b4-1+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase 3' processing activity				Eur J Med Chem 43: 81-92 (2008) Article DOI: 10.1016/j.ejmech.2007.02.021 BindingDB Entry DOI: 10.7270/Q24170XZ
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50087423 ((E)-2-(3,4-dihydroxy-5-iodostyryl)-8-hydroxyquinol...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3cc(O)c(O)c(I)c3)nc2c1O Show InChI InChI=1S/C18H12INO5/c19-13-7-9(8-14(21)17(13)23)1-4-11-5-2-10-3-6-12(18(24)25)16(22)15(10)20-11/h1-8,21-23H,(H,24,25)/b4-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair