BDBM50087424 (E)-8-hydroxy-2-(4-hydroxy-3,5-dimethoxystyryl)quinoline-7-carboxylic acid::8-Hydroxy-2-[2-(4-hydroxy-3,5-dimethoxy-phenyl)-vinyl]-quinoline-7-carboxylic acid::8-hydroxy-2-(4-hydroxy-3,5-dimethoxystyryl)quinoline-7-carboxylic acid::CHEMBL37431

SMILES: COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(OC)c1O

InChI Key: InChIKey=JAYZCPRQQOZLMY-ZZXKWVIFSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50087424   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50087424 ((E)-8-hydroxy-2-(4-hydroxy-3,5-dimethoxystyryl)qui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(OC)c1O Show InChI InChI=1S/C20H17NO6/c1-26-15-9-11(10-16(27-2)19(15)23)3-6-13-7-4-12-5-8-14(20(24)25)18(22)17(12)21-13/h3-10,22-23H,1-2H3,(H,24,25)/b6-3+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087424 ((E)-8-hydroxy-2-(4-hydroxy-3,5-dimethoxystyryl)qui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(OC)c1O Show InChI InChI=1S/C20H17NO6/c1-26-15-9-11(10-16(27-2)19(15)23)3-6-13-7-4-12-5-8-14(20(24)25)18(22)17(12)21-13/h3-10,22-23H,1-2H3,(H,24,25)/b6-3+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase 3' processing activity				Eur J Med Chem 43: 81-92 (2008) Article DOI: 10.1016/j.ejmech.2007.02.021 BindingDB Entry DOI: 10.7270/Q24170XZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50087424 ((E)-8-hydroxy-2-(4-hydroxy-3,5-dimethoxystyryl)qui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(OC)c1O Show InChI InChI=1S/C20H17NO6/c1-26-15-9-11(10-16(27-2)19(15)23)3-6-13-7-4-12-5-8-14(20(24)25)18(22)17(12)21-13/h3-10,22-23H,1-2H3,(H,24,25)/b6-3+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris Sud Curated by ChEMBL					Assay Description Inhibition of PIM1				Bioorg Med Chem Lett 20: 2801-5 (2010) Article DOI: 10.1016/j.bmcl.2010.03.061 BindingDB Entry DOI: 10.7270/Q2125STS
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50087424 ((E)-8-hydroxy-2-(4-hydroxy-3,5-dimethoxystyryl)qui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(OC)c1O Show InChI InChI=1S/C20H17NO6/c1-26-15-9-11(10-16(27-2)19(15)23)3-6-13-7-4-12-5-8-14(20(24)25)18(22)17(12)21-13/h3-10,22-23H,1-2H3,(H,24,25)/b6-3+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair