BDBM50087430 (E)-2-(2-(furan-2-yl)vinyl)-8-hydroxyquinoline-7-carboxylic acid::2-(2-Furan-2-yl-vinyl)-8-hydroxy-quinoline-7-carboxylic acid::CHEMBL38420

SMILES: OC(=O)c1ccc2ccc(\C=C\c3ccco3)nc2c1O

InChI Key: InChIKey=FFXMPJHREREBSJ-VOTSOKGWSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50087430 ((E)-2-(2-(furan-2-yl)vinyl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccco3)nc2c1O Show InChI InChI=1S/C16H11NO4/c18-15-13(16(19)20)8-4-10-3-5-11(17-14(10)15)6-7-12-2-1-9-21-12/h1-9,18H,(H,19,20)/b7-6+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in strand transfer(integration) was tested in CEM cells				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087430 ((E)-2-(2-(furan-2-yl)vinyl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccco3)nc2c1O Show InChI InChI=1S/C16H11NO4/c18-15-13(16(19)20)8-4-10-3-5-11(17-14(10)15)6-7-12-2-1-9-21-12/h1-9,18H,(H,19,20)/b7-6+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase 3' processing activity				Eur J Med Chem 43: 81-92 (2008) Article DOI: 10.1016/j.ejmech.2007.02.021 BindingDB Entry DOI: 10.7270/Q24170XZ
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50087430 ((E)-2-(2-(furan-2-yl)vinyl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccco3)nc2c1O Show InChI InChI=1S/C16H11NO4/c18-15-13(16(19)20)8-4-10-3-5-11(17-14(10)15)6-7-12-2-1-9-21-12/h1-9,18H,(H,19,20)/b7-6+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in 3'-end- processing was tested in CEM cells				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair