BDBM50087432 8-Hydroxy-2-[2-(4-nitro-phenyl)-vinyl]-quinoline-7-carboxylic acid::8-hydroxy-2-(4-nitrostyryl)quinoline-7-carboxylic acid::CHEMBL431508

SMILES: OC(=O)c1ccc2ccc(\C=C\c3ccc(cc3)[N+]([O-])=O)nc2c1O

InChI Key: InChIKey=KWRMAQBKSXXWNB-LZCJLJQNSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50087432   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50087432 (8-Hydroxy-2-[2-(4-nitro-phenyl)-vinyl]-quinoline-7...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(cc3)[N+]([O-])=O)nc2c1O Show InChI InChI=1S/C18H12N2O5/c21-17-15(18(22)23)10-5-12-4-7-13(19-16(12)17)6-1-11-2-8-14(9-3-11)20(24)25/h1-10,21H,(H,22,23)/b6-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087432 (8-Hydroxy-2-[2-(4-nitro-phenyl)-vinyl]-quinoline-7...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(cc3)[N+]([O-])=O)nc2c1O Show InChI InChI=1S/C18H12N2O5/c21-17-15(18(22)23)10-5-12-4-7-13(19-16(12)17)6-1-11-2-8-14(9-3-11)20(24)25/h1-10,21H,(H,22,23)/b6-1+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase 3' processing activity				Eur J Med Chem 43: 81-92 (2008) Article DOI: 10.1016/j.ejmech.2007.02.021 BindingDB Entry DOI: 10.7270/Q24170XZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50087432 (8-Hydroxy-2-[2-(4-nitro-phenyl)-vinyl]-quinoline-7...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(cc3)[N+]([O-])=O)nc2c1O Show InChI InChI=1S/C18H12N2O5/c21-17-15(18(22)23)10-5-12-4-7-13(19-16(12)17)6-1-11-2-8-14(9-3-11)20(24)25/h1-10,21H,(H,22,23)/b6-1+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris Sud Curated by ChEMBL					Assay Description Inhibition of PIM1				Bioorg Med Chem Lett 20: 2801-5 (2010) Article DOI: 10.1016/j.bmcl.2010.03.061 BindingDB Entry DOI: 10.7270/Q2125STS
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087432 (8-Hydroxy-2-[2-(4-nitro-phenyl)-vinyl]-quinoline-7...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(cc3)[N+]([O-])=O)nc2c1O Show InChI InChI=1S/C18H12N2O5/c21-17-15(18(22)23)10-5-12-4-7-13(19-16(12)17)6-1-11-2-8-14(9-3-11)20(24)25/h1-10,21H,(H,22,23)/b6-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair