BDBM50087433 4-[2-(5,7-Dichloro-8-hydroxy-quinolin-2-yl)-vinyl]-benzene-1,2-diol::CHEMBL39725

SMILES: Oc1ccc(\C=C\c2ccc3c(Cl)cc(Cl)c(O)c3n2)cc1O

InChI Key: InChIKey=GKVMHOHBRUCKOQ-HNQUOIGGSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50087433 (4-[2-(5,7-Dichloro-8-hydroxy-quinolin-2-yl)-vinyl]...) Show SMILES Oc1ccc(\C=C\c2ccc3c(Cl)cc(Cl)c(O)c3n2)cc1O Show InChI InChI=1S/C17H11Cl2NO3/c18-12-8-13(19)17(23)16-11(12)5-4-10(20-16)3-1-9-2-6-14(21)15(22)7-9/h1-8,21-23H/b3-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087433 (4-[2-(5,7-Dichloro-8-hydroxy-quinolin-2-yl)-vinyl]...) Show SMILES Oc1ccc(\C=C\c2ccc3c(Cl)cc(Cl)c(O)c3n2)cc1O Show InChI InChI=1S/C17H11Cl2NO3/c18-12-8-13(19)17(23)16-11(12)5-4-10(20-16)3-1-9-2-6-14(21)15(22)7-9/h1-8,21-23H/b3-1+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase 3' processing activity				Eur J Med Chem 43: 81-92 (2008) Article DOI: 10.1016/j.ejmech.2007.02.021 BindingDB Entry DOI: 10.7270/Q24170XZ
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50087433 (4-[2-(5,7-Dichloro-8-hydroxy-quinolin-2-yl)-vinyl]...) Show SMILES Oc1ccc(\C=C\c2ccc3c(Cl)cc(Cl)c(O)c3n2)cc1O Show InChI InChI=1S/C17H11Cl2NO3/c18-12-8-13(19)17(23)16-11(12)5-4-10(20-16)3-1-9-2-6-14(21)15(22)7-9/h1-8,21-23H/b3-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair