BDBM50087434 8-Hydroxy-2-(2-thiophen-3-yl-vinyl)-quinoline-7-carboxylic acid::CHEMBL287903

SMILES: OC(=O)c1ccc2ccc(\C=C\c3ccsc3)nc2c1O

InChI Key: InChIKey=YYMVOSVRYNIAHZ-DAFODLJHSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087434   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50087434 (8-Hydroxy-2-(2-thiophen-3-yl-vinyl)-quinoline-7-ca...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccsc3)nc2c1O Show InChI InChI=1S/C16H11NO3S/c18-15-13(16(19)20)6-3-11-2-5-12(17-14(11)15)4-1-10-7-8-21-9-10/h1-9,18H,(H,19,20)/b4-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087434 (8-Hydroxy-2-(2-thiophen-3-yl-vinyl)-quinoline-7-ca...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccsc3)nc2c1O Show InChI InChI=1S/C16H11NO3S/c18-15-13(16(19)20)6-3-11-2-5-12(17-14(11)15)4-1-10-7-8-21-9-10/h1-9,18H,(H,19,20)/b4-1+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase 3' processing activity				Eur J Med Chem 43: 81-92 (2008) Article DOI: 10.1016/j.ejmech.2007.02.021 BindingDB Entry DOI: 10.7270/Q24170XZ
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50087434 (8-Hydroxy-2-(2-thiophen-3-yl-vinyl)-quinoline-7-ca...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccsc3)nc2c1O Show InChI InChI=1S/C16H11NO3S/c18-15-13(16(19)20)6-3-11-2-5-12(17-14(11)15)4-1-10-7-8-21-9-10/h1-9,18H,(H,19,20)/b4-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair