BDBM50087550 Biphenyl-2-carboxylic acid [3-chloro-4-(5,6,7,8-tetrahydro-thieno[3,2-b]azepine-4-carbonyl)-phenyl]-amide::CHEMBL347020

SMILES: Clc1cc(NC(=O)c2ccccc2-c2ccccc2)ccc1C(=O)N1CCCCc2sccc12

InChI Key: InChIKey=DSUZCBIISAIOSU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50087550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50087550 (Biphenyl-2-carboxylic acid [3-chloro-4-(5,6,7,8-te...) Show SMILES Clc1cc(NC(=O)c2ccccc2-c2ccccc2)ccc1C(=O)N1CCCCc2sccc12 Show InChI InChI=1S/C28H23ClN2O2S/c29-24-18-20(30-27(32)22-11-5-4-10-21(22)19-8-2-1-3-9-19)13-14-23(24)28(33)31-16-7-6-12-26-25(31)15-17-34-26/h1-5,8-11,13-15,17-18H,6-7,12,16H2,(H,30,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro binding affinity to human V1a receptor				Bioorg Med Chem Lett 10: 695-8 (2000) BindingDB Entry DOI: 10.7270/Q2X34WP8
					More data for this Ligand-Target Pair
Vasopressin V2 Receptor (Rattus norvegicus (Rat))	BDBM50087550 (Biphenyl-2-carboxylic acid [3-chloro-4-(5,6,7,8-te...) Show SMILES Clc1cc(NC(=O)c2ccccc2-c2ccccc2)ccc1C(=O)N1CCCCc2sccc12 Show InChI InChI=1S/C28H23ClN2O2S/c29-24-18-20(30-27(32)22-11-5-4-10-21(22)19-8-2-1-3-9-19)13-14-23(24)28(33)31-16-7-6-12-26-25(31)15-17-34-26/h1-5,8-11,13-15,17-18H,6-7,12,16H2,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity to rat V2 receptor				Bioorg Med Chem Lett 10: 695-8 (2000) BindingDB Entry DOI: 10.7270/Q2X34WP8
					More data for this Ligand-Target Pair