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BDBM50087782 3-{3-[(Benzyl-ethoxycarbonylmethyl-amino)-methyl]-5-carbamoyl-phenyl}-acrylic acid ethyl ester::CHEMBL296742

SMILES: CCOC(=O)CN(Cc1ccccc1)Cc1cc(\C=C\C(=O)OCC)cc(c1)C(N)=O

InChI Key: InChIKey=BWJUYOKJHKEVGO-ZHACJKMWSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50087782   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Human rhinovirus A protease


(Human rhinovirus B)		BDBM50087782
PNG
(3-{3-[(Benzyl-ethoxycarbonylmethyl-amino)-methyl]-...)
Show SMILES CCOC(=O)CN(Cc1ccccc1)Cc1cc(\C=C\C(=O)OCC)cc(c1)C(N)=O
Show InChI InChI=1S/C24H28N2O5/c1-3-30-22(27)11-10-19-12-20(14-21(13-19)24(25)29)16-26(17-23(28)31-4-2)15-18-8-6-5-7-9-18/h5-14H,3-4,15-17H2,1-2H3,(H2,25,29)/b11-10+
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



Agouron Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Antiviral activity using H1HeLa cells (ATCC) infected with HRV-14

J Med Chem 43: 1670-83 (2000)


BindingDB Entry DOI: 10.7270/Q2GX49ST
More data for this
Ligand-Target Pair