BDBM50088012 CHEMBL3426973

SMILES: Cc1cc(cc(C)c1Oc1ccnc(NC2CCN(CC(=O)Nc3ccccc3[N+]([O-])=O)CC2)n1)C#N

InChI Key: InChIKey=MTVCWSVICUVQIK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50088012 (CHEMBL3426973) Show SMILES Cc1cc(cc(C)c1Oc1ccnc(NC2CCN(CC(=O)Nc3ccccc3[N+]([O-])=O)CC2)n1)C#N Show InChI InChI=1S/C26H27N7O4/c1-17-13-19(15-27)14-18(2)25(17)37-24-7-10-28-26(31-24)29-20-8-11-32(12-9-20)16-23(34)30-21-5-3-4-6-22(21)33(35)36/h3-7,10,13-14,20H,8-9,11-12,16H2,1-2H3,(H,30,34)(H,28,29,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	193	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 assessed as reduction in biotin-labeled dUTP incorporation into DNA using poly...				Eur J Med Chem 97: 1-9 (2015) Article DOI: 10.1016/j.ejmech.2015.04.050 BindingDB Entry DOI: 10.7270/Q22Z178R
					More data for this Ligand-Target Pair