BDBM50088963 7-{6-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-2-isopropyl-benzoimidazol-1-ylmethyl}-naphthalene-2-carboxamidine::CHEMBL177142

SMILES: CC(C)c1nc2ccc(OC3CCN(CC3)C(C)=N)cc2n1Cc1ccc2ccc(cc2c1)C(N)=N

InChI Key: InChIKey=LOITXWAIWLBDGR-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088963   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50088963 (7-{6-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-2-isopr...) Show SMILES CC(C)c1nc2ccc(OC3CCN(CC3)C(C)=N)cc2n1Cc1ccc2ccc(cc2c1)C(N)=N Show InChI InChI=1S/C29H34N6O/c1-18(2)29-33-26-9-8-25(36-24-10-12-34(13-11-24)19(3)30)16-27(26)35(29)17-20-4-5-21-6-7-22(28(31)32)15-23(21)14-20/h4-9,14-16,18,24,30H,10-13,17H2,1-3H3,(H3,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.0260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Coagulation factor X				Bioorg Med Chem Lett 10: 963-6 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6X0N
					More data for this Ligand-Target Pair
Trypsin (Bos taurus (bovine))	BDBM50088963 (7-{6-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-2-isopr...) Show SMILES CC(C)c1nc2ccc(OC3CCN(CC3)C(C)=N)cc2n1Cc1ccc2ccc(cc2c1)C(N)=N Show InChI InChI=1S/C29H34N6O/c1-18(2)29-33-26-9-8-25(36-24-10-12-34(13-11-24)19(3)30)16-27(26)35(29)17-20-4-5-21-6-7-22(28(31)32)15-23(21)14-20/h4-9,14-16,18,24,30H,10-13,17H2,1-3H3,(H3,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description In vitro inhibitory activity against bovine cationic trypsin				Bioorg Med Chem Lett 10: 963-6 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6X0N
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50088963 (7-{6-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-2-isopr...) Show SMILES CC(C)c1nc2ccc(OC3CCN(CC3)C(C)=N)cc2n1Cc1ccc2ccc(cc2c1)C(N)=N Show InChI InChI=1S/C29H34N6O/c1-18(2)29-33-26-9-8-25(36-24-10-12-34(13-11-24)19(3)30)16-27(26)35(29)17-20-4-5-21-6-7-22(28(31)32)15-23(21)14-20/h4-9,14-16,18,24,30H,10-13,17H2,1-3H3,(H3,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description In vitro inhibitory activity against human coagulation factor II				Bioorg Med Chem Lett 10: 963-6 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6X0N
					More data for this Ligand-Target Pair