BDBM50090696 7-Methyl-2-phenyl-4-piperazin-1-yl-[1,8]naphthyridine::CHEMBL96617

SMILES: Cc1ccc2c(cc(nc2n1)-c1ccccc1)N1CCNCC1

InChI Key: InChIKey=ZVMUIZUYPSGHHR-UHFFFAOYSA-N

Data: 7 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50090696   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine A1 receptor (BOVINE)	BDBM50090696 (7-Methyl-2-phenyl-4-piperazin-1-yl-[1,8]naphthyrid...) Show SMILES Cc1ccc2c(cc(nc2n1)-c1ccccc1)N1CCNCC1 Show InChI InChI=1S/C19H20N4/c1-14-7-8-16-18(23-11-9-20-10-12-23)13-17(22-19(16)21-14)15-5-3-2-4-6-15/h2-8,13,20H,9-12H2,1H3	PDB Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor in bovine cortical membranes using [3H]-CHA as radioligand				J Med Chem 47: 3019-31 (2004) Article DOI: 10.1021/jm030977p BindingDB Entry DOI: 10.7270/Q2BC3Z07
					More data for this Ligand-Target Pair
Adenosine A1 receptor (BOVINE)	BDBM50090696 (7-Methyl-2-phenyl-4-piperazin-1-yl-[1,8]naphthyrid...) Show SMILES Cc1ccc2c(cc(nc2n1)-c1ccccc1)N1CCNCC1 Show InChI InChI=1S/C19H20N4/c1-14-7-8-16-18(23-11-9-20-10-12-23)13-17(22-19(16)21-14)15-5-3-2-4-6-15/h2-8,13,20H,9-12H2,1H3	PDB Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Ability to displace the specific binding of [3H]CHA to adenosine A1 receptor from bovine brain cortical membranes				J Med Chem 43: 2814-23 (2000) BindingDB Entry DOI: 10.7270/Q21R6R6K
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50090696 (7-Methyl-2-phenyl-4-piperazin-1-yl-[1,8]naphthyrid...) Show SMILES Cc1ccc2c(cc(nc2n1)-c1ccccc1)N1CCNCC1 Show InChI InChI=1S/C19H20N4/c1-14-7-8-16-18(23-11-9-20-10-12-23)13-17(22-19(16)21-14)15-5-3-2-4-6-15/h2-8,13,20H,9-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Ability to displace the specific binding of [3H]-CGS- to adenosine A2A receptor form bovine brain striatal membranes				J Med Chem 43: 2814-23 (2000) BindingDB Entry DOI: 10.7270/Q21R6R6K
					More data for this Ligand-Target Pair
Adenosine receptor A2a and A3 (Rattus norvegicus)	BDBM50090696 (7-Methyl-2-phenyl-4-piperazin-1-yl-[1,8]naphthyrid...) Show SMILES Cc1ccc2c(cc(nc2n1)-c1ccccc1)N1CCNCC1 Show InChI InChI=1S/C19H20N4/c1-14-7-8-16-18(23-11-9-20-10-12-23)13-17(22-19(16)21-14)15-5-3-2-4-6-15/h2-8,13,20H,9-12H2,1H3	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Ability to displace the specific binding of [3H](R)-PIA to adenosine A3 receptor from rat testis membranes				J Med Chem 43: 2814-23 (2000) BindingDB Entry DOI: 10.7270/Q21R6R6K
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50090696 (7-Methyl-2-phenyl-4-piperazin-1-yl-[1,8]naphthyrid...) Show SMILES Cc1ccc2c(cc(nc2n1)-c1ccccc1)N1CCNCC1 Show InChI InChI=1S/C19H20N4/c1-14-7-8-16-18(23-11-9-20-10-12-23)13-17(22-19(16)21-14)15-5-3-2-4-6-15/h2-8,13,20H,9-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity against adenosine A2 receptor in bovine striatal membranes using [3H]-CGS-21,680 as radioligand				J Med Chem 47: 3019-31 (2004) Article DOI: 10.1021/jm030977p BindingDB Entry DOI: 10.7270/Q2BC3Z07
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50090696 (7-Methyl-2-phenyl-4-piperazin-1-yl-[1,8]naphthyrid...) Show SMILES Cc1ccc2c(cc(nc2n1)-c1ccccc1)N1CCNCC1 Show InChI InChI=1S/C19H20N4/c1-14-7-8-16-18(23-11-9-20-10-12-23)13-17(22-19(16)21-14)15-5-3-2-4-6-15/h2-8,13,20H,9-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity against adenosine A2 receptor in human striatal membranes using [3H]-CGS-21,680 as radioligand				J Med Chem 47: 3019-31 (2004) Article DOI: 10.1021/jm030977p BindingDB Entry DOI: 10.7270/Q2BC3Z07
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50090696 (7-Methyl-2-phenyl-4-piperazin-1-yl-[1,8]naphthyrid...) Show SMILES Cc1ccc2c(cc(nc2n1)-c1ccccc1)N1CCNCC1 Show InChI InChI=1S/C19H20N4/c1-14-7-8-16-18(23-11-9-20-10-12-23)13-17(22-19(16)21-14)15-5-3-2-4-6-15/h2-8,13,20H,9-12H2,1H3	PDB Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor in human cortical membranes using [3H]-CHA as radioligand				J Med Chem 47: 3019-31 (2004) Article DOI: 10.1021/jm030977p BindingDB Entry DOI: 10.7270/Q2BC3Z07
					More data for this Ligand-Target Pair