BDBM50091067 2-[2-Methoxy-4-(3-phenyl-propyl)-phenyl]-1-methyl-ethylamine::CHEMBL105381
SMILES: COc1cc(CCCc2ccccc2)ccc1CC(C)N
InChI Key: InChIKey=ZGGKVIHEOVKYJK-UHFFFAOYSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50091067 (2-[2-Methoxy-4-(3-phenyl-propyl)-phenyl]-1-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin as radioligand | J Med Chem 44: 3283-91 (2001) BindingDB Entry DOI: 10.7270/Q2MW2GFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50091067 (2-[2-Methoxy-4-(3-phenyl-propyl)-phenyl]-1-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity against human progesterone receptor (hPR) in a competitive binding assay | J Med Chem 60: 2605-2628 (2017) Article DOI: 10.1021/acs.jmedchem.7b00085 BindingDB Entry DOI: 10.7270/Q2DJ5HWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50091067 (2-[2-Methoxy-4-(3-phenyl-propyl)-phenyl]-1-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Displacement of [3H]-ketanserin from NIH3T3 cells stably expressing rat 5-hydroxytryptamine 2A receptor | J Med Chem 43: 3074-84 (2000) BindingDB Entry DOI: 10.7270/Q2NZ86VW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50091067 (2-[2-Methoxy-4-(3-phenyl-propyl)-phenyl]-1-methyl-...) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand | J Med Chem 44: 3283-91 (2001) BindingDB Entry DOI: 10.7270/Q2MW2GFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50091067 (2-[2-Methoxy-4-(3-phenyl-propyl)-phenyl]-1-methyl-...) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Displacement of [3H]-mesulergine from A9 cells stably expressing rat 5-hydroxytryptamine 2C receptor | J Med Chem 43: 3074-84 (2000) BindingDB Entry DOI: 10.7270/Q2NZ86VW | |||||||||||
More data for this Ligand-Target Pair |