BDBM50091110 CHEMBL107414::Cyclopentyl-(2-m-tolyl-2H-pyrazolo[3,4-c]quinolin-4-yl)-amine

SMILES: Cc1cccc(c1)-n1cc2c(n1)c(NC1CCCC1)nc1ccccc21

InChI Key: InChIKey=IYHWVIKQMKGZOE-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50091110 (CHEMBL107414 | Cyclopentyl-(2-m-tolyl-2H-pyrazolo[...) Show SMILES Cc1cccc(c1)-n1cc2c(n1)c(NC1CCCC1)nc1ccccc21 Show InChI InChI=1S/C22H22N4/c1-15-7-6-10-17(13-15)26-14-19-18-11-4-5-12-20(18)24-22(21(19)25-26)23-16-8-2-3-9-16/h4-7,10-14,16H,2-3,8-9H2,1H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	22.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in CHO cells				J Med Chem 43: 3118-24 (2000) BindingDB Entry DOI: 10.7270/Q28S4P52
					More data for this Ligand-Target Pair
Adenosine A1 receptor (BOVINE)	BDBM50091110 (CHEMBL107414 | Cyclopentyl-(2-m-tolyl-2H-pyrazolo[...) Show SMILES Cc1cccc(c1)-n1cc2c(n1)c(NC1CCCC1)nc1ccccc21 Show InChI InChI=1S/C22H22N4/c1-15-7-6-10-17(13-15)26-14-19-18-11-4-5-12-20(18)24-22(21(19)25-26)23-16-8-2-3-9-16/h4-7,10-14,16H,2-3,8-9H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	40.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of specific [3H]-CHA binding at adenosine A1 receptor in bovine brain membranes				J Med Chem 43: 3118-24 (2000) BindingDB Entry DOI: 10.7270/Q28S4P52
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50091110 (CHEMBL107414 | Cyclopentyl-(2-m-tolyl-2H-pyrazolo[...) Show SMILES Cc1cccc(c1)-n1cc2c(n1)c(NC1CCCC1)nc1ccccc21 Show InChI InChI=1S/C22H22N4/c1-15-7-6-10-17(13-15)26-14-19-18-11-4-5-12-20(18)24-22(21(19)25-26)23-16-8-2-3-9-16/h4-7,10-14,16H,2-3,8-9H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of specific [3H]-CGS- 21680 binding at Adenosine A2A receptor in bovine striatal membranes.				J Med Chem 43: 3118-24 (2000) BindingDB Entry DOI: 10.7270/Q28S4P52
					More data for this Ligand-Target Pair