BDBM50091130 2-m-Tolyl-2H-pyrazolo[3,4-c]quinolin-4-ylamine::2-m-tolyl-2H-pyrazolo[3,4-c]quinolin-4-amine::CHEMBL107446

SMILES: Cc1cccc(c1)-n1cc2c(n1)c(N)nc1ccccc21

InChI Key: InChIKey=NJFGXLMDWIXVEW-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50091130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50091130 (2-m-Tolyl-2H-pyrazolo[3,4-c]quinolin-4-ylamine | 2...) Show SMILES Cc1cccc(c1)-n1cc2c(n1)c(N)nc1ccccc21 Show InChI InChI=1S/C17H14N4/c1-11-5-4-6-12(9-11)21-10-14-13-7-2-3-8-15(13)19-17(18)16(14)20-21/h2-10H,1H3,(H2,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells				J Med Chem 50: 4061-74 (2007) Article DOI: 10.1021/jm070123v BindingDB Entry DOI: 10.7270/Q2JM29BR
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50091130 (2-m-Tolyl-2H-pyrazolo[3,4-c]quinolin-4-ylamine | 2...) Show SMILES Cc1cccc(c1)-n1cc2c(n1)c(N)nc1ccccc21 Show InChI InChI=1S/C17H14N4/c1-11-5-4-6-12(9-11)21-10-14-13-7-2-3-8-15(13)19-17(18)16(14)20-21/h2-10H,1H3,(H2,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	99.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in CHO cells				J Med Chem 43: 3118-24 (2000) BindingDB Entry DOI: 10.7270/Q28S4P52
					More data for this Ligand-Target Pair
Adenosine A1 receptor (BOVINE)	BDBM50091130 (2-m-Tolyl-2H-pyrazolo[3,4-c]quinolin-4-ylamine | 2...) Show SMILES Cc1cccc(c1)-n1cc2c(n1)c(N)nc1ccccc21 Show InChI InChI=1S/C17H14N4/c1-11-5-4-6-12(9-11)21-10-14-13-7-2-3-8-15(13)19-17(18)16(14)20-21/h2-10H,1H3,(H2,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of specific [3H]-CHA binding at adenosine A1 receptor in bovine brain membranes				J Med Chem 43: 3118-24 (2000) BindingDB Entry DOI: 10.7270/Q28S4P52
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50091130 (2-m-Tolyl-2H-pyrazolo[3,4-c]quinolin-4-ylamine | 2...) Show SMILES Cc1cccc(c1)-n1cc2c(n1)c(N)nc1ccccc21 Show InChI InChI=1S/C17H14N4/c1-11-5-4-6-12(9-11)21-10-14-13-7-2-3-8-15(13)19-17(18)16(14)20-21/h2-10H,1H3,(H2,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	228	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cells				J Med Chem 50: 4061-74 (2007) Article DOI: 10.1021/jm070123v BindingDB Entry DOI: 10.7270/Q2JM29BR
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50091130 (2-m-Tolyl-2H-pyrazolo[3,4-c]quinolin-4-ylamine | 2...) Show SMILES Cc1cccc(c1)-n1cc2c(n1)c(N)nc1ccccc21 Show InChI InChI=1S/C17H14N4/c1-11-5-4-6-12(9-11)21-10-14-13-7-2-3-8-15(13)19-17(18)16(14)20-21/h2-10H,1H3,(H2,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of specific [3H]-CGS- 21680 binding at Adenosine A2A receptor in bovine striatal membranes.				J Med Chem 43: 3118-24 (2000) BindingDB Entry DOI: 10.7270/Q28S4P52
					More data for this Ligand-Target Pair