BDBM50091143 CHEMBL106986::Phenethyl-(2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-yl)-amine

SMILES: C(Cc1ccccc1)Nc1nc2ccccc2c2cn(nc12)-c1ccccc1

InChI Key: InChIKey=CYSDHZJPDQKSJB-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50091143 (CHEMBL106986 | Phenethyl-(2-phenyl-2H-pyrazolo[3,4...) Show SMILES C(Cc1ccccc1)Nc1nc2ccccc2c2cn(nc12)-c1ccccc1 Show InChI InChI=1S/C24H20N4/c1-3-9-18(10-4-1)15-16-25-24-23-21(20-13-7-8-14-22(20)26-24)17-28(27-23)19-11-5-2-6-12-19/h1-14,17H,15-16H2,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in CHO cells				J Med Chem 43: 3118-24 (2000) BindingDB Entry DOI: 10.7270/Q28S4P52
					More data for this Ligand-Target Pair
Adenosine A1 receptor (BOVINE)	BDBM50091143 (CHEMBL106986 | Phenethyl-(2-phenyl-2H-pyrazolo[3,4...) Show SMILES C(Cc1ccccc1)Nc1nc2ccccc2c2cn(nc12)-c1ccccc1 Show InChI InChI=1S/C24H20N4/c1-3-9-18(10-4-1)15-16-25-24-23-21(20-13-7-8-14-22(20)26-24)17-28(27-23)19-11-5-2-6-12-19/h1-14,17H,15-16H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	60.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of specific [3H]-CHA binding at adenosine A1 receptor in bovine brain membranes				J Med Chem 43: 3118-24 (2000) BindingDB Entry DOI: 10.7270/Q28S4P52
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50091143 (CHEMBL106986 | Phenethyl-(2-phenyl-2H-pyrazolo[3,4...) Show SMILES C(Cc1ccccc1)Nc1nc2ccccc2c2cn(nc12)-c1ccccc1 Show InChI InChI=1S/C24H20N4/c1-3-9-18(10-4-1)15-16-25-24-23-21(20-13-7-8-14-22(20)26-24)17-28(27-23)19-11-5-2-6-12-19/h1-14,17H,15-16H2,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of specific [3H]-CGS- 21680 binding at Adenosine A2A receptor in bovine striatal membranes.				J Med Chem 43: 3118-24 (2000) BindingDB Entry DOI: 10.7270/Q28S4P52
					More data for this Ligand-Target Pair