BDBM50091394 1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-ethanone O-benzyl-oxime::CHEMBL324123

SMILES: C\C(=N/OCc1ccccc1)c1ccc(OCCCc2cnc[nH]2)cc1

InChI Key: InChIKey=JHBSXNBQQPVNCJ-JJIBRWJFSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091394   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091394 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-ethano...) Show SMILES C\C(=N/OCc1ccccc1)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C21H23N3O2/c1-17(24-26-15-18-6-3-2-4-7-18)19-9-11-21(12-10-19)25-13-5-8-20-14-22-16-23-20/h2-4,6-7,9-12,14,16H,5,8,13,15H2,1H3,(H,22,23)/b24-17+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair