BDBM50091641 5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1H-indazole::CHEMBL114644

SMILES: C(C#Cc1ccc2[nH]ncc2c1)N1CCC(Cc2ccccc2)CC1

InChI Key: InChIKey=KIDRVLWOPFGWLW-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50091641 (5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1H-ind...) Show SMILES C(C#Cc1ccc2[nH]ncc2c1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H23N3/c1-2-5-18(6-3-1)15-20-10-13-25(14-11-20)12-4-7-19-8-9-22-21(16-19)17-23-24-22/h1-3,5-6,8-9,16-17,20H,10-15H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description Concentration required for 50% Inhibition of responses at cloned NR1A/2A NMDA expressed in Xenopus oocytes				J Med Chem 43: 3408-19 (2000) BindingDB Entry DOI: 10.7270/Q2VH5N26
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50091641 (5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1H-ind...) Show SMILES C(C#Cc1ccc2[nH]ncc2c1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H23N3/c1-2-5-18(6-3-1)15-20-10-13-25(14-11-20)12-4-7-19-8-9-22-21(16-19)17-23-24-22/h1-3,5-6,8-9,16-17,20H,10-15H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description Concentration required for 50% Inhibition of responses at cloned NR1A/2C NMDA expressed in Xenopus oocytes				J Med Chem 43: 3408-19 (2000) BindingDB Entry DOI: 10.7270/Q2VH5N26
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50091641 (5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1H-ind...) Show SMILES C(C#Cc1ccc2[nH]ncc2c1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H23N3/c1-2-5-18(6-3-1)15-20-10-13-25(14-11-20)12-4-7-19-8-9-22-21(16-19)17-23-24-22/h1-3,5-6,8-9,16-17,20H,10-15H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes				J Med Chem 43: 3408-19 (2000) BindingDB Entry DOI: 10.7270/Q2VH5N26
					More data for this Ligand-Target Pair