BDBM50091919 1-(3-tert-Butyl-isoxazol-5-yl)-3-(2,3-dichloro-phenyl)-urea::CHEMBL292482

SMILES: CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)on1

InChI Key: InChIKey=AURAQYYVUVMTGJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50091919 (1-(3-tert-Butyl-isoxazol-5-yl)-3-(2,3-dichloro-phe...) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)on1 Show InChI InChI=1S/C14H15Cl2N3O2/c1-14(2,3)10-7-11(21-19-10)18-13(20)17-9-6-4-5-8(15)12(9)16/h4-7H,1-3H3,(H2,17,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2 expressed in E. coli.				Bioorg Med Chem Lett 10: 2047-50 (2000) BindingDB Entry DOI: 10.7270/Q2FB526H
					More data for this Ligand-Target Pair