BDBM50092286 5-[(E)-3-(4-Dimethylamino-phenyl)-prop-2-en-(Z)-ylidene]-2-thioxo-thiazolidin-4-one::CHEMBL69676

SMILES: CN(C)c1ccc(C=CC=C2SC(S)=NC2=O)cc1

InChI Key: InChIKey=NUIRQBZFPKGTRR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-lactamase (Enterobacter cloacae)	BDBM50092286 (5-[(E)-3-(4-Dimethylamino-phenyl)-prop-2-en-(Z)-yl...) Show SMILES CN(C)c1ccc(C=CC=C2SC(S)=NC2=O)cc1 |w:9.8,7.6,c:13| Show InChI InChI=1S/C14H14N2OS2/c1-16(2)11-8-6-10(7-9-11)4-3-5-12-13(17)15-14(18)19-12/h3-9H,1-2H3,(H,15,17,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against class C Beta-lactamase isolated from Enterobacter cloacae				Bioorg Med Chem Lett 10: 2179-82 (2001) BindingDB Entry DOI: 10.7270/Q2T15456
					More data for this Ligand-Target Pair
Beta-lactamase TEM (Enterobacter cloacae)	BDBM50092286 (5-[(E)-3-(4-Dimethylamino-phenyl)-prop-2-en-(Z)-yl...) Show SMILES CN(C)c1ccc(C=CC=C2SC(S)=NC2=O)cc1 |w:9.8,7.6,c:13| Show InChI InChI=1S/C14H14N2OS2/c1-16(2)11-8-6-10(7-9-11)4-3-5-12-13(17)15-14(18)19-12/h3-9H,1-2H3,(H,15,17,18)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against class A Beta-lactamase TEM isolated from Enterobacter coli				Bioorg Med Chem Lett 10: 2179-82 (2001) BindingDB Entry DOI: 10.7270/Q2T15456
					More data for this Ligand-Target Pair