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BDBM50092428 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-phenyl-tetrahydro-pyrimidin-2-one::CHEMBL123139

SMILES: O=C1N(CCC2CCN(CC3COc4ccccc4O3)CC2)CCCN1c1ccccc1

InChI Key: InChIKey=FFXZAVMSBRRUNZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092428   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50092428
PNG
(1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-...)
Show SMILES O=C1N(CCC2CCN(CC3COc4ccccc4O3)CC2)CCCN1c1ccccc1
Show InChI InChI=1S/C26H33N3O3/c30-26-28(14-6-15-29(26)22-7-2-1-3-8-22)18-13-21-11-16-27(17-12-21)19-23-20-31-24-9-4-5-10-25(24)32-23/h1-5,7-10,21,23H,6,11-20H2
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PubMed
n/an/a 38n/an/an/an/an/an/a



Centre de Recherche Pierre Fabre

Curated by ChEMBL


Assay Description
In vitro inhibition of specific binding of [3H]-YM 09151-2 to Dopamine receptor D2 site in rat striatal tissue.

J Med Chem 43: 3653-64 (2000)


BindingDB Entry DOI: 10.7270/Q2MW2GD3
More data for this
Ligand-Target Pair