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BDBM50092435 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-(2,4,6-trimethoxy-phenyl)-imidazolidin-2-one::CHEMBL121262

SMILES: COc1cc(OC)c(N2CCN(CCC3CCN(CC4COc5ccccc5O4)CC3)C2=O)c(OC)c1

InChI Key: InChIKey=PBLAPYRVHBZQPW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092435   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50092435
PNG
(1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-...)
Show SMILES COc1cc(OC)c(N2CCN(CCC3CCN(CC4COc5ccccc5O4)CC3)C2=O)c(OC)c1
Show InChI InChI=1S/C28H37N3O6/c1-33-21-16-25(34-2)27(26(17-21)35-3)31-15-14-30(28(31)32)13-10-20-8-11-29(12-9-20)18-22-19-36-23-6-4-5-7-24(23)37-22/h4-7,16-17,20,22H,8-15,18-19H2,1-3H3
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PubMed
n/an/a 320n/an/an/an/an/an/a



Centre de Recherche Pierre Fabre

Curated by ChEMBL


Assay Description
In vitro inhibition of specific binding of [3H]-YM 09151-2 to Dopamine receptor D2 site in rat striatal tissue.

J Med Chem 43: 3653-64 (2000)


BindingDB Entry DOI: 10.7270/Q2MW2GD3
More data for this
Ligand-Target Pair