BDBM50092503 4,6-dimethyl-8-methyl-1,2,5,6-tetrahydro pyrido[1,2-a]quinolin-3-one::CHEMBL125257

SMILES: CC1CC2=C(C)C(=O)CCN2c2ccc(C)cc12

InChI Key: InChIKey=VJNBCORATKDAPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092503   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5α-Reductase 1 (5α-R1) (Homo sapiens (Human))	BDBM50092503 (4,6-dimethyl-8-methyl-1,2,5,6-tetrahydro pyrido[1,...) Show SMILES CC1CC2=C(C)C(=O)CCN2c2ccc(C)cc12 |c:3| Show InChI InChI=1S/C16H19NO/c1-10-4-5-14-13(8-10)11(2)9-15-12(3)16(18)6-7-17(14)15/h4-5,8,11H,6-7,9H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant Steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair