BDBM50094543 5,7-Diphenyl-2,3-dihydro-1H-pyrrolizine::CHEMBL143523

SMILES: C1Cc2c(cc(-c3ccccc3)n2C1)-c1ccccc1

InChI Key: InChIKey=ACTKECOOJAVUPF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50094543   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase-2 (COX-2) (Mus musculus (Mouse))	BDBM50094543 (5,7-Diphenyl-2,3-dihydro-1H-pyrrolizine | CHEMBL14...) Show SMILES C1Cc2c(cc(-c3ccccc3)n2C1)-c1ccccc1 Show InChI InChI=1S/C19H17N/c1-3-8-15(9-4-1)17-14-19(16-10-5-2-6-11-16)20-13-7-12-18(17)20/h1-6,8-11,14H,7,12-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair