BDBM50094552 1,3-Diphenyl-benzo[c]thiophene::CHEMBL143653
SMILES: c1ccc(cc1)-c1sc(-c2ccccc2)c2ccccc12
InChI Key: InChIKey=RQXSNTYLVXFUAA-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclooxygenase-2 (COX-2) (Mus musculus (Mouse)) | BDBM50094552![]() (1,3-Diphenyl-benzo[c]thiophene | CHEMBL143653) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 10.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase (cyclooxygenase) (Mus musculus) | BDBM50094552![]() (1,3-Diphenyl-benzo[c]thiophene | CHEMBL143653) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair |