null
SMILES: Fc1ccc(cc1)-c1[nH]c(c2C3CC(C=C3)c12)-c1ccc(F)cc1
InChI Key: InChIKey=IMVOJEMXLCTUSD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094561 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094561 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.51 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr HS Gour University Curated by ChEMBL | Assay Description Inhibition of mouse macrophage COX2 | Eur J Med Chem 43: 1559-69 (2008) Article DOI: 10.1016/j.ejmech.2007.09.028 BindingDB Entry DOI: 10.7270/Q2M909WP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094561 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair |