BDBM50094564 3,5-di(4-pyridyl)-4-azatricyclo[5.2.1.02,6]deca-2,5-diene; dihydrochloride::CHEMBL544620

SMILES: C1CC2CC1c1c2c([nH]c1-c1ccncc1)-c1ccncc1

InChI Key: InChIKey=FFXNDPPBECHBAJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50094564   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase-2 (COX-2) (Mus musculus (Mouse))	BDBM50094564 (3,5-di(4-pyridyl)-4-azatricyclo[5.2.1.02,6]deca-2,...) Show SMILES C1CC2CC1c1c2c([nH]c1-c1ccncc1)-c1ccncc1 Show InChI InChI=1S/C19H17N3/c1-2-15-11-14(1)16-17(15)19(13-5-9-21-10-6-13)22-18(16)12-3-7-20-8-4-12/h3-10,14-15,22H,1-2,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair