BDBM50095122 CHEMBL3589518
SMILES: CCn1c(nc2cc(NC(=O)COC)cc(C(=O)NCc3ccccc3)c12)-c1cccnc1
InChI Key: InChIKey=SIXRWSUKYNSLRT-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Inhibin beta A chain (Mus musculus) | BDBM50095122 (CHEMBL3589518) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at activin A in mouse LbetaT2 cells transfected with -338 promoter region of FSHbeta gene conjugated to luciferase reporter asses... | J Med Chem 58: 5637-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00753 BindingDB Entry DOI: 10.7270/Q2RF5WSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth/differentiation factor 8 (Mus musculus) | BDBM50095122 (CHEMBL3589518) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.79E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at myostatin in mouse LbetaT2 cells transfected with -338 promoter region of FSHbeta gene conjugated to luciferase reporter asses... | J Med Chem 58: 5637-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00753 BindingDB Entry DOI: 10.7270/Q2RF5WSW | |||||||||||
More data for this Ligand-Target Pair |