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SMILES: COc1ccc(OC[C@@H](O)CN2CCC(O)CC2)c(CNCCc2cccnc2)c1

InChI Key: InChIKey=NBHQNPDLNQQPDZ-NRFANRHFSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50095126   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inhibin beta A chain


(Mus musculus)		BDBM50095126
PNG
(CHEMBL3589514)
Show SMILES COc1ccc(OC[C@@H](O)CN2CCC(O)CC2)c(CNCCc2cccnc2)c1 |r|
Show InChI InChI=1S/C23H33N3O4/c1-29-22-4-5-23(30-17-21(28)16-26-11-7-20(27)8-12-26)19(13-22)15-25-10-6-18-3-2-9-24-14-18/h2-5,9,13-14,20-21,25,27-28H,6-8,10-12,15-17H2,1H3/t21-/m0/s1
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.18E+3n/an/an/an/an/an/a



Northwestern University

Curated by ChEMBL


Assay Description
Antagonist activity at activin A in mouse LbetaT2 cells transfected with -338 promoter region of FSHbeta gene conjugated to luciferase reporter asses...

J Med Chem 58: 5637-48 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00753
BindingDB Entry DOI: 10.7270/Q2RF5WSW
More data for this
Ligand-Target Pair