BDBM50095140 CHEMBL3589516
SMILES: Cn1cc(CN2C[C@@H](CN(Cc3ccc(cc3)C#CC(C)(C)O)CC2=O)OCc2cccnc2)cn1
InChI Key: InChIKey=AXLBTHPTIVQLAP-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Inhibin beta A chain (Mus musculus) | BDBM50095140![]() (CHEMBL3589516) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at activin A in mouse LbetaT2 cells transfected with -338 promoter region of FSHbeta gene conjugated to luciferase reporter asses... | J Med Chem 58: 5637-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00753 BindingDB Entry DOI: 10.7270/Q2RF5WSW | |||||||||||
More data for this Ligand-Target Pair |