BDBM50095297 CHEMBL3589086
SMILES: CC(=N)NCc1cccc(CNC(=O)CC(O)=O)c1
InChI Key: InChIKey=KKUKTBVEYAJFEF-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric Oxide Synthase, inducible (Mus musculus (mouse)) | BDBM50095297![]() (CHEMBL3589086) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Chieti"G. d'Annunzio" Curated by ChEMBL | Assay Description Inhibition of mouse recombinant iNOS using [3H]L-arginine substrate assessed as formation of [3H]L-citruline by liquid scintillation counting analysi... | ACS Med Chem Lett 6: 635-40 (2015) Article DOI: 10.1021/acsmedchemlett.5b00149 BindingDB Entry DOI: 10.7270/Q2C53NKC | |||||||||||
More data for this Ligand-Target Pair |