BDBM50095326 2-Methoxy-5-(3,4,5-trimethoxy-phenoxy)-phenol::CHEMBL356370

SMILES: COc1ccc(Oc2cc(OC)c(OC)c(OC)c2)cc1O

InChI Key: InChIKey=OJRSPUQFMNDPAN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50095326 (2-Methoxy-5-(3,4,5-trimethoxy-phenoxy)-phenol | CH...) Show SMILES COc1ccc(Oc2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C16H18O6/c1-18-13-6-5-10(7-12(13)17)22-11-8-14(19-2)16(21-4)15(9-11)20-3/h5-9,17H,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Salford Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of tubulin polymerization				J Med Chem 48: 457-65 (2005) Article DOI: 10.1021/jm049444m BindingDB Entry DOI: 10.7270/Q2416WKV
					More data for this Ligand-Target Pair
Tubulin (Sus scrofa (Pig))	BDBM50095326 (2-Methoxy-5-(3,4,5-trimethoxy-phenoxy)-phenol | CH...) Show SMILES COc1ccc(Oc2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C16H18O6/c1-18-13-6-5-10(7-12(13)17)22-11-8-14(19-2)16(21-4)15(9-11)20-3/h5-9,17H,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Concentration required to cause 50% decrease in the binding of [3H]colchicine from purified porcine tubulin.				Bioorg Med Chem Lett 11: 51-4 (2001) BindingDB Entry DOI: 10.7270/Q2C82CHT
					More data for this Ligand-Target Pair
Tubulin (Sus scrofa (Pig))	BDBM50095326 (2-Methoxy-5-(3,4,5-trimethoxy-phenoxy)-phenol | CH...) Show SMILES COc1ccc(Oc2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C16H18O6/c1-18-13-6-5-10(7-12(13)17)22-11-8-14(19-2)16(21-4)15(9-11)20-3/h5-9,17H,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Effect on tubulin binding and the concentration required to cause 50% decrease in tubulin assembly at 350 nm.				Bioorg Med Chem Lett 11: 51-4 (2001) BindingDB Entry DOI: 10.7270/Q2C82CHT
					More data for this Ligand-Target Pair