BDBM50095566 4-Morpholin-4-yl-1-(4-phenoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL421766

SMILES: ONC(=O)[C@H]1C[C@@H](CN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1)N1CCOCC1

InChI Key: InChIKey=MTGNBEKVSCTMSE-OXJNMPFZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50095566 (4-Morpholin-4-yl-1-(4-phenoxy-benzenesulfonyl)-pyr...) Show SMILES ONC(=O)[C@H]1C[C@@H](CN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1)N1CCOCC1 Show InChI InChI=1S/C21H25N3O6S/c25-21(22-26)20-14-16(23-10-12-29-13-11-23)15-24(20)31(27,28)19-8-6-18(7-9-19)30-17-4-2-1-3-5-17/h1-9,16,20,26H,10-15H2,(H,22,25)/t16-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloproteinase -1 (collagenase-1)				J Med Chem 43: 4948-63 (2001) BindingDB Entry DOI: 10.7270/Q21N80DW
					More data for this Ligand-Target Pair
Matrix metalloproteinase-7 (MMP7) (Homo sapiens (Human))	BDBM50095566 (4-Morpholin-4-yl-1-(4-phenoxy-benzenesulfonyl)-pyr...) Show SMILES ONC(=O)[C@H]1C[C@@H](CN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1)N1CCOCC1 Show InChI InChI=1S/C21H25N3O6S/c25-21(22-26)20-14-16(23-10-12-29-13-11-23)15-24(20)31(27,28)19-8-6-18(7-9-19)30-17-4-2-1-3-5-17/h1-9,16,20,26H,10-15H2,(H,22,25)/t16-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloproteinase-7 (matrilysin, MMP-7)				J Med Chem 43: 4948-63 (2001) BindingDB Entry DOI: 10.7270/Q21N80DW
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50095566 (4-Morpholin-4-yl-1-(4-phenoxy-benzenesulfonyl)-pyr...) Show SMILES ONC(=O)[C@H]1C[C@@H](CN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1)N1CCOCC1 Show InChI InChI=1S/C21H25N3O6S/c25-21(22-26)20-14-16(23-10-12-29-13-11-23)15-24(20)31(27,28)19-8-6-18(7-9-19)30-17-4-2-1-3-5-17/h1-9,16,20,26H,10-15H2,(H,22,25)/t16-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloproteinase -3 (stromelysin)				J Med Chem 43: 4948-63 (2001) BindingDB Entry DOI: 10.7270/Q21N80DW
					More data for this Ligand-Target Pair