BDBM50095568 1-(4-Butoxy-benzenesulfonyl)-4-(2-hydroxy-propionylamino)-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL356520
SMILES: CCCCOc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@@H]1C(=O)NO)NC(=O)[C@H](C)O
InChI Key: InChIKey=SBIQGLZKCCTUIC-HEHGZKQESA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Matrix metalloproteinase-7 (MMP7) (Homo sapiens (Human)) | BDBM50095568 (1-(4-Butoxy-benzenesulfonyl)-4-(2-hydroxy-propiony...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against matrix metalloproteinase-7 (matrilysin, MMP-7) | J Med Chem 43: 4948-63 (2001) BindingDB Entry DOI: 10.7270/Q21N80DW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interstitial collagenase (Homo sapiens (Human)) | BDBM50095568 (1-(4-Butoxy-benzenesulfonyl)-4-(2-hydroxy-propiony...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against matrix metalloproteinase -1 (collagenase-1) | J Med Chem 43: 4948-63 (2001) BindingDB Entry DOI: 10.7270/Q21N80DW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM50095568 (1-(4-Butoxy-benzenesulfonyl)-4-(2-hydroxy-propiony...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against human recombinant matrix metalloproteinase-13 (collagenase-3) | J Med Chem 43: 4948-63 (2001) BindingDB Entry DOI: 10.7270/Q21N80DW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM50095568 (1-(4-Butoxy-benzenesulfonyl)-4-(2-hydroxy-propiony...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against matrix metalloproteinase -3 (stromelysin) | J Med Chem 43: 4948-63 (2001) BindingDB Entry DOI: 10.7270/Q21N80DW | |||||||||||
More data for this Ligand-Target Pair |