BDBM50096551 CHEMBL327484::N-Methyl-N-[2-phenyl-4-(4-phenyl-piperidin-1-yl)-butyl]-benzenesulfonamide

SMILES: CN(CC(CCN1CCC(CC1)c1ccccc1)c1ccccc1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=UETIGXLCWMKVCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50096551 (CHEMBL327484 | N-Methyl-N-[2-phenyl-4-(4-phenyl-pi...) Show SMILES CN(CC(CCN1CCC(CC1)c1ccccc1)c1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C28H34N2O2S/c1-29(33(31,32)28-15-9-4-10-16-28)23-27(25-13-7-3-8-14-25)19-22-30-20-17-26(18-21-30)24-11-5-2-6-12-24/h2-16,26-27H,17-23H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [125I]-MIP-1 alpha to human CCR5 receptor.				Bioorg Med Chem Lett 11: 265-70 (2001) BindingDB Entry DOI: 10.7270/Q2668CFZ
					More data for this Ligand-Target Pair