BDBM50096562 CHEMBL90691::N-[2-(3,5-Dichloro-phenyl)-4-(4-phenyl-piperidin-1-yl)-butyl]-N-methyl-benzenesulfonamide

SMILES: CN(CC(CCN1CCC(CC1)c1ccccc1)c1cc(Cl)cc(Cl)c1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=WIBBPDXGCMFKBV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096562   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50096562 (CHEMBL90691 | N-[2-(3,5-Dichloro-phenyl)-4-(4-phen...) Show SMILES CN(CC(CCN1CCC(CC1)c1ccccc1)c1cc(Cl)cc(Cl)c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C28H32Cl2N2O2S/c1-31(35(33,34)28-10-6-3-7-11-28)21-24(25-18-26(29)20-27(30)19-25)14-17-32-15-12-23(13-16-32)22-8-4-2-5-9-22/h2-11,18-20,23-24H,12-17,21H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [125I]-MIP-1 alpha to human CCR5 receptor.				Bioorg Med Chem Lett 11: 265-70 (2001) BindingDB Entry DOI: 10.7270/Q2668CFZ
					More data for this Ligand-Target Pair