BDBM50096567 CHEMBL329190::N-Methyl-N-[2-naphthalen-2-yl-4-(4-phenyl-piperidin-1-yl)-butyl]-benzenesulfonamide

SMILES: CN(CC(CCN1CCC(CC1)c1ccccc1)c1ccc2ccccc2c1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=DZNWWHDJWHTPPT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50096567 (CHEMBL329190 | N-Methyl-N-[2-naphthalen-2-yl-4-(4-...) Show SMILES CN(CC(CCN1CCC(CC1)c1ccccc1)c1ccc2ccccc2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C32H36N2O2S/c1-33(37(35,36)32-14-6-3-7-15-32)25-31(30-17-16-27-12-8-9-13-29(27)24-30)20-23-34-21-18-28(19-22-34)26-10-4-2-5-11-26/h2-17,24,28,31H,18-23,25H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [125I]-MIP-1 alpha to human CCR5 receptor.				Bioorg Med Chem Lett 11: 265-70 (2001) BindingDB Entry DOI: 10.7270/Q2668CFZ
					More data for this Ligand-Target Pair