null

SMILES: CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H]1CCc2ccccc12

InChI Key: InChIKey=FGDQQAHGMHOQDV-NGXZDTIWSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50097248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50097248 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-indan-1-ylcarbam...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H]1CCc2ccccc12 Show InChI InChI=1S/C28H34N4O4/c1-17(2)13-19(15-26(33)32-36)27(34)31-25(14-20-16-29-23-10-6-5-9-22(20)23)28(35)30-24-12-11-18-7-3-4-8-21(18)24/h3-10,16-17,19,24-25,29,36H,11-15H2,1-2H3,(H,30,35)(H,31,34)(H,32,33)/t19-,24+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description Binding affinity towards 72 kDa gelatinase (Matrix metalloproteinase-2)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50097248 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-indan-1-ylcarbam...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H]1CCc2ccccc12 Show InChI InChI=1S/C28H34N4O4/c1-17(2)13-19(15-26(33)32-36)27(34)31-25(14-20-16-29-23-10-6-5-9-22(20)23)28(35)30-24-12-11-18-7-3-4-8-21(18)24/h3-10,16-17,19,24-25,29,36H,11-15H2,1-2H3,(H,30,35)(H,31,34)(H,32,33)/t19-,24+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloproteinase-8)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50097248 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-indan-1-ylcarbam...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H]1CCc2ccccc12 Show InChI InChI=1S/C28H34N4O4/c1-17(2)13-19(15-26(33)32-36)27(34)31-25(14-20-16-29-23-10-6-5-9-22(20)23)28(35)30-24-12-11-18-7-3-4-8-21(18)24/h3-10,16-17,19,24-25,29,36H,11-15H2,1-2H3,(H,30,35)(H,31,34)(H,32,33)/t19-,24+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-2				Bioorg Med Chem Lett 11: 567-70 (2001) BindingDB Entry DOI: 10.7270/Q2610ZK1
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50097248 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-indan-1-ylcarbam...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H]1CCc2ccccc12 Show InChI InChI=1S/C28H34N4O4/c1-17(2)13-19(15-26(33)32-36)27(34)31-25(14-20-16-29-23-10-6-5-9-22(20)23)28(35)30-24-12-11-18-7-3-4-8-21(18)24/h3-10,16-17,19,24-25,29,36H,11-15H2,1-2H3,(H,30,35)(H,31,34)(H,32,33)/t19-,24+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50097248 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-indan-1-ylcarbam...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H]1CCc2ccccc12 Show InChI InChI=1S/C28H34N4O4/c1-17(2)13-19(15-26(33)32-36)27(34)31-25(14-20-16-29-23-10-6-5-9-22(20)23)28(35)30-24-12-11-18-7-3-4-8-21(18)24/h3-10,16-17,19,24-25,29,36H,11-15H2,1-2H3,(H,30,35)(H,31,34)(H,32,33)/t19-,24+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-3				Bioorg Med Chem Lett 11: 567-70 (2001) BindingDB Entry DOI: 10.7270/Q2610ZK1
					More data for this Ligand-Target Pair