null

SMILES: CC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ncccn1

InChI Key: InChIKey=OHIMWQXBTPNPOS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097345   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50097345 (3-Methyl-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...) Show SMILES CC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 |t:1| Show InChI InChI=1S/C22H27N5O2/c1-18-17-29-20-8-3-2-7-19(20)21(28)27(18)12-5-4-11-25-13-15-26(16-14-25)22-23-9-6-10-24-22/h2-3,6-10,17H,4-5,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligand				Bioorg Med Chem Lett 11: 595-8 (2001) BindingDB Entry DOI: 10.7270/Q2P26XDB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50097345 (3-Methyl-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...) Show SMILES CC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 |t:1| Show InChI InChI=1S/C22H27N5O2/c1-18-17-29-20-8-3-2-7-19(20)21(28)27(18)12-5-4-11-25-13-15-26(16-14-25)22-23-9-6-10-24-22/h2-3,6-10,17H,4-5,11-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 11: 595-8 (2001) BindingDB Entry DOI: 10.7270/Q2P26XDB
					More data for this Ligand-Target Pair