BDBM50097434 CHEMBL435866::N-(2-Phenyl-quinazolin-4-yl)-benzamide

SMILES: O=C(Nc1nc(nc2ccccc12)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=OTUOIHJJRAPDOB-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097434   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50097434 (CHEMBL435866 | N-(2-Phenyl-quinazolin-4-yl)-benzam...) Show SMILES O=C(Nc1nc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C21H15N3O/c25-21(16-11-5-2-6-12-16)24-20-17-13-7-8-14-18(17)22-19(23-20)15-9-3-1-4-10-15/h1-14H,(H,22,23,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in HEK 293 cells				J Med Chem 44: 749-62 (2001) BindingDB Entry DOI: 10.7270/Q2H132Q0
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family G member 2 (Homo sapiens (Human))	BDBM50097434 (CHEMBL435866 | N-(2-Phenyl-quinazolin-4-yl)-benzam...) Show SMILES O=C(Nc1nc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C21H15N3O/c25-21(16-11-5-2-6-12-16)24-20-17-13-7-8-14-18(17)22-19(23-20)15-9-3-1-4-10-15/h1-14H,(H,22,23,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	424	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of GFP-fused human ABCG2 expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins followed by Hoechst 3334...				Eur J Med Chem 161: 506-525 (2019) Article DOI: 10.1016/j.ejmech.2018.10.026
					More data for this Ligand-Target Pair