BDBM50097933 CHEMBL85468::Sulfamic acid 4-[(E)-(3-phenyl-acryloyl)]-phenyl ester

SMILES: NS(=O)(=O)Oc1ccc(cc1)C(=O)\C=C\c1ccccc1

InChI Key: InChIKey=OHRKDOLDPKANJQ-IZZDOVSWSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Steryl-sulfatase (Homo sapiens (Human))	BDBM50097933 (CHEMBL85468 | Sulfamic acid 4-[(E)-(3-phenyl-acryl...) Show SMILES NS(=O)(=O)Oc1ccc(cc1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C15H13NO4S/c16-21(18,19)20-14-9-7-13(8-10-14)15(17)11-6-12-4-2-1-3-5-12/h1-11H,(H2,16,18,19)/b11-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Punjabi University Curated by ChEMBL					Assay Description Inhibition of placental microsomal estrone sulfatase (unknown origin) using [3H]-estrone sulphate as substrate incubated for 20 mins by scintillation...				Eur J Med Chem 114: 170-90 (2016) BindingDB Entry DOI: 10.7270/Q26Q2048
					More data for this Ligand-Target Pair
Steryl-sulfatase (Homo sapiens (Human))	BDBM50097933 (CHEMBL85468 | Sulfamic acid 4-[(E)-(3-phenyl-acryl...) Show SMILES NS(=O)(=O)Oc1ccc(cc1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C15H13NO4S/c16-21(18,19)20-14-9-7-13(8-10-14)15(17)11-6-12-4-2-1-3-5-12/h1-11H,(H2,16,18,19)/b11-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.63E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kingston University Curated by ChEMBL					Assay Description Inhibition of Estrone sulfatase				Bioorg Med Chem Lett 11: 841-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8FFS
					More data for this Ligand-Target Pair
Steryl-sulfatase (Homo sapiens (Human))	BDBM50097933 (CHEMBL85468 | Sulfamic acid 4-[(E)-(3-phenyl-acryl...) Show SMILES NS(=O)(=O)Oc1ccc(cc1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C15H13NO4S/c16-21(18,19)20-14-9-7-13(8-10-14)15(17)11-6-12-4-2-1-3-5-12/h1-11H,(H2,16,18,19)/b11-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.63E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kingston University Curated by ChEMBL					Assay Description Inhibition of estrone sulfatase (ES)				Bioorg Med Chem Lett 11: 2525-8 (2001) BindingDB Entry DOI: 10.7270/Q2CF9QMP
					More data for this Ligand-Target Pair