BDBM50097950 7-Cyclobutyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine::7-cyclobutyl-5-(4-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine::CHEMBL169079

SMILES: COc1ccc(cc1)-c1cn(C2CCC2)c2ncnc(N)c12

InChI Key: InChIKey=NLRGFJLOCKKPKU-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097950   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Gallus gallus (Chicken))	BDBM50097950 (7-Cyclobutyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-d...) Show SMILES COc1ccc(cc1)-c1cn(C2CCC2)c2ncnc(N)c12 Show InChI InChI=1S/C17H18N4O/c1-22-13-7-5-11(6-8-13)14-9-21(12-3-2-4-12)17-15(14)16(18)19-10-20-17/h5-10,12H,2-4H2,1H3,(H2,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Research Curated by ChEMBL					Assay Description Inhibition of p60 c-Src tyrosine kinase activity				Bioorg Med Chem Lett 11: 849-52 (2001) BindingDB Entry DOI: 10.7270/Q2FF3RMF
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Gallus gallus (Chicken))	BDBM50097950 (7-Cyclobutyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-d...) Show SMILES COc1ccc(cc1)-c1cn(C2CCC2)c2ncnc(N)c12 Show InChI InChI=1S/C17H18N4O/c1-22-13-7-5-11(6-8-13)14-9-21(12-3-2-4-12)17-15(14)16(18)19-10-20-17/h5-10,12H,2-4H2,1H3,(H2,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Research Curated by ChEMBL					Assay Description Inhibition of p60 c-Src tyrosine kinase activity				Bioorg Med Chem Lett 11: 849-52 (2001) BindingDB Entry DOI: 10.7270/Q2FF3RMF
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50097950 (7-Cyclobutyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-d...) Show SMILES COc1ccc(cc1)-c1cn(C2CCC2)c2ncnc(N)c12 Show InChI InChI=1S/C17H18N4O/c1-22-13-7-5-11(6-8-13)14-9-21(12-3-2-4-12)17-15(14)16(18)19-10-20-17/h5-10,12H,2-4H2,1H3,(H2,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of c-Src				Eur J Med Chem 44: 990-1000 (2009) Article DOI: 10.1016/j.ejmech.2008.07.002 BindingDB Entry DOI: 10.7270/Q2ZC8434
					More data for this Ligand-Target Pair