BDBM50097977 CHEMBL367933::[(R)-4-((R)-4-Amino-5-phenyl-pyrrolo[2,3-d]pyrimidin-7-yl)-pyrrolidin-2-yl]-methanol

SMILES: Nc1ncnc2n(cc(-c3ccccc3)c12)[C@@H]1CN[C@@H](CO)C1

InChI Key: InChIKey=CBMZHRLWBJZWAP-OLZOCXBDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50097977 (CHEMBL367933 | [(R)-4-((R)-4-Amino-5-phenyl-pyrrol...) Show SMILES Nc1ncnc2n(cc(-c3ccccc3)c12)[C@@H]1CN[C@@H](CO)C1 Show InChI InChI=1S/C17H19N5O/c18-16-15-14(11-4-2-1-3-5-11)8-22(17(15)21-10-20-16)13-6-12(9-23)19-7-13/h1-5,8,10,12-13,19,23H,6-7,9H2,(H2,18,20,21)/t12-,13+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Research Curated by ChEMBL					Assay Description Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mL				Bioorg Med Chem Lett 11: 853-6 (2001) BindingDB Entry DOI: 10.7270/Q29P30XJ
					More data for this Ligand-Target Pair